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Semax

Approved in Russia, nowhere else. Most of the literature is in Russian and hard to appraise from outside.

Approved in some countries

What it isA synthetic analogue of a fragment of ACTH, developed in Russia.
How it is thought to workReported to raise BDNF and modulate the dopaminergic and serotonergic systems.
What the evidence actually showsUsed clinically in Russia for stroke and cognitive indications. Most published work is Russian-language, with limited independent replication and few trials meeting Western regulatory standards.
Regulatory statusRegistered as a medicine in Russia. Not approved in the US, EU, UK or Canada.
DosingThere is a Russian clinical dosing standard for the intranasal product. It is not an FDA-approved dose and the research-grade material is not that product.
In the catalog as

Risks and cautions

  • Limited independent safety data outside Russia.
  • Interactions with psychiatric medication are not well characterised.

Sources

Before you act on any of this

This page describes what is known and what is not. It is not a recommendation to use anything, and it is not a protocol. Compounds listed as research chemicals are not approved medicines and are not sold for human use. Talk to a doctor who knows your history.